Hexarelin — Vendor Pricing & Purity Guide
Research Overview
Hexarelin (Examorelin) is a synthetic hexapeptide growth hormone secretagogue and one of the most potent GHRPs ever developed. It stimulates GH release through the ghrelin/GHS-R1a receptor with greater potency than GHRP-6 and GHRP-2 on a per-dose basis. However, Hexarelin is notable for a significant limitation: it produces rapid and pronounced desensitization of the GH response, with the effect diminishing substantially within 4-16 weeks of continuous use.
Beyond GH secretion, Hexarelin has demonstrated unique cardioprotective properties. It activates CD36 receptors on cardiac tissue, which are not involved in GH release, providing heart-protective effects independent of its GH-stimulating activity. This has made Hexarelin particularly interesting for cardiac research, where it has shown protective effects against ischemia-reperfusion injury.
Due to its desensitization profile, Hexarelin is not typically used in long-term GH stimulation research. Ipamorelin and CJC-1295 are generally preferred for sustained protocols. However, Hexarelin's potent acute GH stimulation and its unique cardiac activity maintain its research relevance.
Key Research Findings
- •Most potent acute GH release among classical GHRPs in comparative studies
- •Demonstrated cardioprotective effects via CD36 receptor activation independent of GH release
- •Reduced infarct size and improved cardiac function in ischemia-reperfusion injury models
- •Rapid GH response desensitization within 4-16 weeks of continuous administration
- •Elevates cortisol and prolactin more than Ipamorelin but less than GHRP-6 at equivalent doses
Research Dosage Protocols
Hexarelin is supplied as lyophilized powder reconstituted with bacteriostatic water. Doses of 1-2 mcg/kg body weight administered subcutaneously produce significant GH elevation.
Due to the desensitization issue, research protocols with Hexarelin often use intermittent dosing schedules with drug-free intervals rather than continuous daily administration.
For research reference only. Not medical advice. Not for human consumption.
Price Comparison (8 products from 6 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Particle Peptides | $29.99 $6.00/mg 5mg lyophilized | In Stock |
| Skye Peptides | $44.00 $8.80/mg 5mg lyophilized | In Stock |
| Peptide Sciences | $45.00 $9.00/mg 5mg lyophilized | In Stock |
| Core Peptides | $47.00 $9.40/mg 5mg vial | In Stock |
| Peptide Sciences | $95.00 $9.50/mg 10mg lyophilized | In Stock |
| Biotech Peptides | $49.00 $9.80/mg 5mg vial | In Stock |
| Swiss Chems | $21.56 $10.78/mg 2mg vial | In Stock |
| Peptide Sciences | $30.00 $15.00/mg 2mg lyophilized | In Stock |
Frequently Asked Questions
What is Hexarelin?
Hexarelin is the most potent classical GHRP for acute GH release. It also has unique cardioprotective properties via CD36 receptor activation. However, it causes rapid GH response desensitization, limiting its use in long-term protocols.
Why does Hexarelin stop working?
Hexarelin causes pronounced desensitization of the GHS receptor within 4-16 weeks. The GH response diminishes significantly with continuous use. This is more pronounced than with other GHRPs like Ipamorelin.
Where can I buy Hexarelin for research?
Hexarelin is available from research peptide vendors. Compare pricing in the table above.