BPC-157
Research Overview
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a portion of the human gastric juice protein. It consists of 15 amino acids and has been the subject of extensive preclinical research since the 1990s, primarily at the University of Zagreb. Unlike many peptides that require refrigeration and injection, BPC-157 has demonstrated stability at room temperature and activity via multiple routes of administration in animal models.
The peptide's mechanism of action involves upregulation of growth hormone receptors, modulation of the nitric oxide (NO) system, and promotion of angiogenesis — the formation of new blood vessels. It interacts with the FAK-paxillin pathway, which plays a central role in cell migration and tissue repair. Research has also identified effects on the dopaminergic and serotonergic systems, suggesting broader systemic activity beyond localized tissue healing.
BPC-157 is one of the most widely studied and commercially available research peptides. It appears in more vendor catalogs than any other peptide, and is frequently the first compound researchers investigate. Its stability profile and oral bioavailability in rodent models distinguish it from most injectable-only peptides.
Key Research Findings
- •Accelerated healing of muscle, tendon, and ligament injuries in multiple rodent studies (Sikiric et al., 2018)
- •Demonstrated gastroprotective effects comparable to standard anti-ulcer agents in rat models
- •Promoted angiogenesis and granulation tissue formation, accelerating wound closure in animal skin injury models
- •Showed neuroprotective properties in rat models of traumatic brain injury with improved cognitive outcomes
- •Counteracted the toxic effects of NSAIDs on the gut lining in rodent studies
- •Demonstrated activity via oral, subcutaneous, intraperitoneal, and topical administration routes in animal models
- •No reported toxicity in any published rodent study at doses up to 10 mg/kg
Research Dosage Protocols
In published rodent studies, BPC-157 has been administered at doses ranging from 10 mcg/kg to 10 mg/kg body weight, with the most commonly cited research dose being 200-500 mcg/kg via subcutaneous or intraperitoneal injection.
The peptide is typically supplied as a lyophilized powder requiring reconstitution with bacteriostatic water. Standard reconstitution involves adding the appropriate volume of solvent directly to the vial and gently swirling (not shaking) until dissolved. Reconstituted solutions are generally stored at 2-8°C.
Two primary forms are available commercially: the standard acetate salt and the arginine salt (also called "stable BPC-157"). The arginine salt form has improved water solubility and pH stability, which some researchers prefer for oral administration studies. Both forms contain the same active 15-amino-acid sequence.
For research reference only. Not medical advice. Not for human consumption.
Published Research (4 studies)
- [1]
- [2]
- [3]Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon— Staresinic et al., 2006PMID: 16467017
- [4]
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (81 products from 19 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Pure Rawz | $211.18 $0.89/mg 237.75mg capsule | In Stock |
| Peptide Crafters | $80.00 $1.14/mg 70mg lyophilized | In Stock |
| Peptide Crafters | $95.00 $1.19/mg 80mg lyophilized | In Stock |
| Skye Peptides | $69.00 $1.38/mg 50mg lyophilized | In Stock |
| Polaris Peptides | $99.00 $1.98/mg 50mg blend | In Stock |
| Polaris Peptides | $125.00 $2.50/mg 50mg blend | In Stock |
| Polaris Peptides | $89.00 $2.54/mg 35mg blend | In Stock |
| Peptide Crafters | $90.00 $3.00/mg 30mg lyophilized | In Stock |
| BioLongevity Labs | $274.97 $3.44/mg 80mg vial | In Stock |
| Peptide Partners | $245.00 $3.50/mg 70mg | In Stock |
| BioLongevity Labs | $259.97 $3.71/mg 70mg vial | In Stock |
| Paradigm Peptides | $40.00 $4.00/mg 10mg lyophilized | In Stock |
| Astro Peptides | $40.00 $4.00/mg 10mg lyophilized | In Stock |
| Peptide Crafters | $85.00 $4.25/mg 20mg blend | In Stock |
| Core Peptides | $300.00 $4.29/mg 70mg vial | In Stock |
| Biotech Peptides | $305.00 $4.36/mg 70mg vial | In Stock |
| Triumphant Labs | $49.00 $4.90/mg 10mg | In Stock |
| Peptide Sciences | $395.00 $4.94/mg 80mg lyophilized | In Stock |
| Peptide Sciences | $315.00 $5.25/mg 60mg lyophilized | In Stock |
| Peptide Sciences | $165.00 $5.50/mg 30mg lyophilized | In Stock |
| Peptide Crafters | $55.00 $5.50/mg 10mg lyophilized | In Stock |
| Apollo Peptide Sciences | $59.99 $6.00/mg 10mg vial | In Stock |
| Polaris Peptides | $60.00 $6.00/mg 10mg lyophilized | In Stock |
| Triumphant Labs | $62.00 $6.20/mg 10mg | In Stock |
| Pure Rawz | $452.62 $6.29/mg 72mg vial | In Stock |
| Particle Peptides | $31.99 $6.40/mg 5mg lyophilized | In Stock |
| Polaris Peptides | $35.00 $7.00/mg 5mg lyophilized | In Stock |
| Swiss Chems | $39.99 $8.00/mg 5mg vial | In Stock |
| Swiss Chems | $39.99 $8.00/mg 5mg vial | In Stock |
| Pure Rawz | $323.67 $8.41/mg 38.5mg spray | In Stock |
| Pure Rawz | $270.85 $9.03/mg 30mg vial | In Stock |
| BioLongevity Labs | $279.97 $9.33/mg 30mg vial | In Stock |
| BioLongevity Labs | $99.97 $10.00/mg 10mg vial | In Stock |
| Peptide Sciences | $200.00 $10.00/mg 20mg lyophilized | In Stock |
| Core Peptides | $52.00 $10.40/mg 5mg vial | In Stock |
| Biotech Peptides | $52.00 $10.40/mg 5mg vial | In Stock |
| Core Peptides | $105.00 $10.50/mg 10mg vial | In Stock |
| Peptide Partners | $106.00 $10.60/mg 10mg | In Stock |
| Pure Rawz | $164.47 $10.96/mg 15mg vial | In Stock |
| Polaris Peptides | $110.00 $11.00/mg 10mg blend | In Stock |
| Biotech Peptides | $115.00 $11.50/mg 10mg vial | In Stock |
| Peptide Sciences | $59.50 $11.90/mg 5mg lyophilized | In Stock |
| BioLongevity Labs | $119.97 $12.00/mg 10mg vial | In Stock |
| Peptide Sciences | $120.00 $12.00/mg 10mg lyophilized | In Stock |
| Peptide Partners | $255.00 $12.75/mg 20mg | In Stock |
| Swiss Chems | $132.95 $26.59/mg 5mg vial | In Stock |
| Pure Rawz | $350.96 $31.91/mg 11mg vial | In Stock |
| Triumphant Labs | $416.00 $41.60/mg 10mg | In Stock |
| Triumphant Labs | $556.00 $55.60/mg 10mg | In Stock |
| Astro Peptides | $560.00 $56.00/mg 10mg lyophilized | In Stock |
| Astro Peptides | $320.00 $64.00/mg 5mg lyophilized | In Stock |
| Astro Peptides | $1008.00 $100.80/mg 10mg lyophilized | In Stock |
| Swiss Chems | $85.95 $171.90/mg 0.5mg capsule | In Stock |
| NextChems | $85.95 $171.90/mg 0.5mg capsule | In Stock |
| Skye Peptides | $89.00 $178.00/mg 0.5mg capsule | In Stock |
| Peptide Sciences | $165.00 $330.00/mg 0.5mg capsule | In Stock |
| Simple Peptide | $170.00 $340.00/mg 0.5mg capsule | In Stock |
| Simple Peptide | $170.00 $340.00/mg 0.5mg capsule | In Stock |
| Limitless Biotech | $157.00 $628.00/mg 0.25mg capsule | Out |
| BioLongevity Labs | $249.97 $833.23/mg 0.3mg vial | In Stock |
| Peptide Sciences | $325.00 capsule | In Stock |
| Peptide Sciences | $300.00 capsule | In Stock |
| Limitless Biotech | $157.00 spray | Out |
| Limitless Biotech | $157.00 lyophilized | Out |
| Limitless Biotech | $157.00 spray | Out |
| Limitless Biotech | $157.00 lyophilized | Out |
| Limitless Biotech | $157.00 lyophilized | Out |
| Pure Rawz | $98.12 vial | In Stock |
| Soma Chems | $109.99 vial | In Stock |
| Soma Chems | $49.99 spray | In Stock |
| Soma Chems | $69.99 vial | In Stock |
| Soma Chems | $39.99 vial | In Stock |
| Skye Peptides | $129.00 lyophilized | In Stock |
| Skye Peptides | $94.00 lyophilized | In Stock |
| Skye Peptides | $64.00 blend | In Stock |
| Skye Peptides | $49.00 lyophilized | In Stock |
| Simple Peptide | $68.00 lyophilized | In Stock |
| Simple Peptide | $140.00 blend | In Stock |
| Simple Peptide | $115.00 blend | In Stock |
| Simple Peptide | $55.00 blend | In Stock |
| Paradigm Peptides | $75.00 blend | In Stock |
Frequently Asked Questions
What is BPC-157?
BPC-157 is a synthetic 15-amino-acid peptide derived from a naturally occurring protein found in human gastric juice. It has been studied extensively in animal models for tissue repair, gut healing, and neuroprotection.
Where can I buy BPC-157 for research?
BPC-157 is available from multiple research peptide vendors. We track pricing across all major suppliers — see the price comparison table above for current rates sorted by cost per milligram.
What is the difference between BPC-157 and BPC-157 Arginine Salt?
Both contain the same 15-amino-acid peptide sequence. The arginine salt form has improved water solubility and pH stability, making it more suitable for oral administration research. The standard acetate salt is more common for injection-based studies.
Has BPC-157 been tested in humans?
As of 2025, no peer-reviewed human clinical trials have been published for BPC-157. All existing research is from animal models, primarily rodent studies. A Phase I trial (NCT05765747) has been registered but results have not yet been published.
How should BPC-157 be stored?
Lyophilized (powder) BPC-157 is stable at room temperature for extended periods. Once reconstituted with bacteriostatic water, it should be stored at 2-8°C (refrigerated) and used within 4-6 weeks.